This work presents a monopolar-and-bipolar super-reconfigurable 16-channel neurostimulation IC with active charge-balancing (ACB) and on-chip power management achieving 12-V compliance voltage in a 180-nm standard CMOS process. A novel dynamically self-biased stimulation driver ensures circuit reliability while supporting monopolar-and-bipolar bimodal operations. The proposed ACB scheme allows automatic residual charge removal in a self-controlled loop with minimum system complexity overhead. A 2.2-to-3.3-V-input reconfigurable charge-pump-based power management unit is implemented to generate ±6 V outputs, which extends the stimulation compliance voltage to 12 V in bipolar modes. The peak power efficiencies of the ±6-V charge-pumps are measured to be 75.07% and 58.25%, respectively. The ACB module is measured to reduce the residue voltage to less than 2 mV for both polarities. The proposed neurostimulation IC offers exceptional reconfigurability, power efficiency, and system integrity, addressing the evolving demands of modern neuromodulation devices.
该工作提出了一款单极性与双极性超高可重构16通道神经刺激芯片，集成主动电荷平衡（active charge balancing，ACB）和片上电源管理，基于180 nm标准CMOS工艺实现了12 V的顺应电压。所提出的新型动态自偏置刺激驱动器在保证电路可靠性的同时，支持单极性与双极性两种工作模式。所提出的ACB方案采用自控制闭环，可在系统复杂度开销最小的情况下实现残余电荷的自动消除。芯片中实现了一款输入电压范围为2.2～3.3 V的可重构电荷泵电源管理单元，用于产生**±6 V输出电压**，从而将双极性工作模式下的刺激顺应电压扩展至12 V。±6 V电荷泵的峰值功率效率实测分别达到75.07%和58.25%。实测结果表明，ACB模块可将正、负两个极性的残余电压均降低至2 mV以下。所提出的神经刺激芯片具有出色的可重构性、功率效率和系统完整性，能够满足现代神经调控设备不断演进的需求。
